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Recent experimental measurements of muonic bound states provide a new powerful way to study the properties of QCD at low energies as well as to probe physics beyond the standard model. These systems are best described by means of an effective field theory, namely potential non-relativistic QED (pNRQED). The well-established power counting of pNRQED allows for model independent predictions while keeping theoretical uncertainties under control. In this talk I will review both the experimental status and the theoretical setting and present the computation of the Lamb shift and the hyperfine splitting in muonic hydrogen, with special emphasis on the hadronic contributions and the determination of the proton radius.